|
Welcome to Top articles Port!
Articles » Health-&-Fitness >> View Article
 
Search your Favorite Articles
|
 |
|
 |
| Cialis (Tadalafil) ICOS |
By:
M-Washman |
|
Tadalafil is a selective inhibitor of cyclic guanosine monophosphate (GMP)-specific phosphodiesterase type 5 (PDE5). The drug is approved for the treatment of erectile dysfunction.
Efficacy. The efficacy and safety of tadalafil was established in 22 clinical trials enrolling more than 4,000 patients. In 2 randomized, multicenter, double-blinded, placebo-controlled, 12-week studies, tadalafil was taken (20 mg QD) by patients enrolled from the general erectile dysfunction (ED) population. The 3 primary outcome measures were the Erectile Function (EF) domain of the International Index of Erectile Function (IIEF) and Questions 2 and 3 from the Sexual Encounter Profile. The IIEF EF domain consists of a 30-point score, where higher scores indicate better erectile function. For the EF domain score outcome in Study A, the tadalafil group demonstrated a 6.9-point change from baseline compared to a 0.2-point change from baseline in the placebo group (P |
|
|
 |
 |
 |
 |
|
|
